Article
The POU gene ceh-18 promotes gonadal sheath cell differentiation and function required for meiotic maturation and ovulation in Caenorhabditis elegans.
Developmental biology - 1 Dec 1997
Rose K L, Winfrey V P, Hoffman L H, Hall D H, Furuta T, Greenstein D
Abstract excerpt
In Caenorhabditis elegans, specialized contractile myoepithelial cells of the somatic gonad, the gonadal sheath cells, are closely apposed to oocytes and are required for normal meiotic maturation and ovulation. Previously we found that mutations in the ceh-18 gene, which encodes a POU-class homeoprotein expressed in sheath cells, result in oocyte defects. To determine the basis for these oocyte defects, we have...
Topics
- Animals
- Caenorhabditis elegans
- Cell Differentiation
- Female
- Haploidy
- Helminth Proteins
- Homeodomain Proteins
- Meiosis
- Microscopy, Electron
- Mutation
- Oocytes
- Ovulation
- Transcription Factors