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Article

Frequency of spontaneous and induced micronuclei in the peripheral blood of aging mice.

Mutation research - 19 Nov 1997

Dass S B, Ali S F, Heflich R H, Casciano D A

Abstract excerpt

The mouse peripheral blood micronucleus assay, a measure of DNA damage in erythroblastic cells, was used to determine: (1) the incidence of spontaneously occurring micronucleated reticulocytes (MNRETs) as a function of age, and (2) the induction of micronuclei following treatment of young and old animals with mitomycin C. Male C57BL/6 mice, 92 weeks of age, exhibited a significantly higher frequency of...

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Identifiers

PMID: 9403036
DOI: 10.1016/s0027-5107(97)00156-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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