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Article

Aneuploidies and micronuclei in the germ cells of male mice of advanced age.

Mutation research - 1 Oct 1995

Lowe X, Collins B, Allen J, Titenko-Holland N, Breneman J, van Beek M, Bishop J, Wyrobek A J

Abstract excerpt

The objective of this research was to determine whether the frequencies of chromosomally defective germ cells increased with age in male laboratory mice. Two types of chromosomal abnormalities were characterized: (1) testicular spermatid aneuploidy (TSA) as measured by a new method of multi-color...

Topics

Aging
Aneuploidy
Animals
Centromere
Chromosome Aberrations
Chromosomes
DNA Probes
In Situ Hybridization, Fluorescence
Male
Mice
Mice, Inbred Strains
Micronuclei, Chromosome-Defective

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Micronucleus Tests

Paternal Age

Phenotype

Sex Chromosomes

Spermatids

Source

Identifiers

PMID: 7565883
DOI: 10.1016/0921-8734(95)00012-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7565883-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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