Article
The effect of donor age on spontaneous and induced micronuclei.
Mutation research - 1 Jan 2000
Fenech M, Morley A A
Abstract excerpt
The spontaneous micronucleus yield in lymphocyte cultures from healthy donors aged 0-82 years was estimated at 72 h and 96 h of culture. At both 72 and 96 h there was a positive correlation of micronucleus expression with increasing age (p less than 0.001), with an approximately 4-fold increase i...
Topics
- Adolescent
- Adult
- Aged
- Aging
- Cell Nucleus
- Cells, Cultured
- Child
- DNA
- Dose-Response Relationship, Drug
- Dose-Response Relationship, Radiation
- Humans
- Infant
- Infant, Newborn
- Lymphocytes
- Middle Aged
- Mitomycin
- Mitomycins
- Mutation