Article
The effect of donor age on spontaneous and induced micronuclei.
Mutation research - 1 Jan 2000
Fenech M, Morley A A
Abstract excerpt
The spontaneous micronucleus yield in lymphocyte cultures from healthy donors aged 0-82 years was estimated at 72 h and 96 h of culture. At both 72 and 96 h there was a positive correlation of micronucleus expression with increasing age (p less than 0.001), with an approximately 4-fold increase in micronuclei in cultures from 80-year-old donors when compared to cultures from newborn donors. Since there is some...
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