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Article

Identification of Strategic Residues at the Interface of Antigen-Antibody Interactions by In Silico Mutagenesis.

Interdisciplinary sciences, computational life sciences - 1 Jun 2018

Xin Lu, Yu Hai, Hong Qiyang, Bi Xingjian, Zhang Xiao, Zhang Zhiqing, Kong Zhibo, Zheng Qingbing, Gu Ying, Zhao Qinjian, Zhang Jun, Li Shaowei, Xia Ningshao

Abstract excerpt

Structural information pertaining to antigen-antibody interactions is fundamental in immunology, and benefits structure-based vaccine design. Modeling of antigen-antibody immune complexes from co-crystal structures or molecular docking simulations provides an extensive profile of the epitope at the interface; however, the key amino acids involved in the interaction must be further clarified, often through the use...

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PMID: 28560699
DOI: 10.1007/s12539-017-0242-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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