Article
Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man.
Circulation - 18 Nov 1997
Sudhir K, Chou T M, Chatterjee K, Smith E P, Williams T C, Kane J P, Malloy M J, Korach K S, Rubanyi G M
Abstract excerpt
BACKGROUND: While estrogens protect against coronary artery disease in women, it is unclear whether they influence cardiovascular function in men. The present report describes coronary vascular abnormalities and the lipoprotein profile of a male patient with estrogen insensitivity caused by a disruptive mutation in the estrogen-receptor gene. METHODS AND RESULTS: Stress thallium scintigraphy, echocardiography,...
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