Article
Analysis of DNA from subjects found to be heterozygous for the haptoglobin-Johnson alpha gene.
Experimental and clinical immunogenetics - 1 Jan 1997
Nagai T, Okazaki T, Yanagisawa Y
Abstract excerpt
We found two rare Hp Johnson variant families (Hp2-Johnson type and Hp1-Johnson type) by PAGE. It was confirmed by SDS-PAGE that the haptoglobin molecules with the Hp Johnson variant consisted of alpha-2 or alpha-1 and alpha-3 subunits. Direct gene analysis of Hp Johnson heterozygous individuals using three endonucleases: EcoRI, HindIII and BamHI, showed a three-fold tandem repeat of the same 1.7-kb DNA fragment...
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