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Article

Identification of Spanish familial Parkinson's disease and screening for the Ala53Thr mutation of the alpha-synuclein gene in early onset patients.

Neuroscience letters - 10 Oct 1997

Muñoz E, Oliva R, Obach V, Martí M J, Pastor P, Ballesta F, Tolosa E

Abstract excerpt

We initiated the present work in order to determine if the Ala53Thr mutation of the alpha-synuclein gene previously described by Polymeropoulos et al. [Science, 276 (1997) 2045-2047] could be detected in Spanish early onset Parkinson's disease (PD) patients. Thirty-four PD patients were evaluated...

Topics

Adult
Aged
Female
Humans
Male
Middle Aged
Mutation
Nerve Tissue Proteins
Parkinson Disease
Pedigree
Polymerase Chain Reaction
Spain
Synucleins

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alpha-Synuclein

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Identifiers

PMID: 9389595
DOI: 10.1016/s0304-3940(97)00710-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9389595-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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