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Article

A tricyclic ring system replaces the variable regions of peptides presented by three alleles of human MHC class I molecules.

Chemistry & biology - 1 Jun 1995

Weiss G A, Collins E J, Garboczi D N, Wiley D C, Schreiber S L

Abstract excerpt

BACKGROUND: Cytotoxic T-lymphocytes (CTLs) recognize complexes of short peptides with major histocompatibility complex (MHC) class I molecules. MHC molecules are polymorphic, and the products of different MHC alleles bind to different subsets of peptides. This is due to differences in the shape of the peptide-binding groove on the surface of the MHC protein, especially the 'pockets' into which anchor residues at...

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Identifiers

PMID: 9383442
DOI: 10.1016/1074-5521(95)90221-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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