Article
Genetic and Molecular Basis of Kingella kingae Encapsulation.
Infection and immunity - 1 Jun 2016
Starr Kimberly F, Porsch Eric A, Seed Patrick C, St Geme Joseph W
Abstract excerpt
Kingella kingae is a common cause of invasive disease in young children and was recently found to produce a polysaccharide capsule containing N-acetylgalactosamine (GalNAc) and β-3-deoxy-d-manno-octulosonic acid (βKdo). Given the role of capsules as important virulence factors and effective vaccine antigens, we set out to determine the genetic determinants of K. kingae encapsulation. Using a transposon library...
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