Article
Recombination initiation: easy as A, B, C, D... chi?
Current biology : CB - 1 Dec 1997
Eggleston A K, West S C
Abstract excerpt
The octameric Chi (chi) sequence is a recombination hotspot in Escherichia coli. Recent studies suggest a singular mechanism by which chi regulates not only the nuclease activity of RecBCD enzyme, but also the ability of RecBCD to promote loading of the strand exchange protein, RecA, onto chi-con...
Topics
- Binding Sites
- DNA, Bacterial
- Escherichia coli
- Exodeoxyribonuclease V
- Exodeoxyribonucleases
- Mutation
- Rec A Recombinases
- Recombination, Genetic