Article
Old and new concepts for the role of chi in bacterial recombination.
The Journal of heredity - 1 Jan 2000
Stahl F, Myers R
Abstract excerpt
The DNA sequence 5'[GCTGGTGG]3', which is called chi, stimulates recombination that is mediated by the RecBCD pathway of Escherichia coli. In 1981, a model was proposed in which the RecBCD enzyme enters DNA at a double-chain end. The enzyme then travels between the chains by unwinding and rewinding the DNA at different rates so that the traveling enzyme becomes encumbered by a region of unwound DNA. Upon meeting...
Topics
- Base Sequence
- DNA Helicases
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Exodeoxyribonuclease V
- Exodeoxyribonucleases
- Mutation
- Recombination, Genetic