Article
Lung resistance protein (LRP) gene expression in adult acute myeloid leukemia: a critical evaluation by three techniques.
Leukemia - 1 Sept 1998
Legrand O, Simonin G, Zittoun R, Marie J P
Abstract excerpt
The role of LRP in clinical drug resistance in acute myeloid leukemia (AML) is controversial. We therefore compared multiple assays, including RT-PCR, immunocytochemistry (ICC) and flow cytometry (FC), in 10 cell lines and in 47 fresh and thawed AML cells in order to validate and to quantitate me...
Topics
- Acute Disease
- Adult
- Antineoplastic Agents
- Cisplatin
- Flow Cytometry
- Humans
- Immunohistochemistry
- Leukemia, Myeloid
- Neoplasm Proteins
- Phenotype
- Polymerase Chain Reaction
- RNA, Messenger
- Reproducibility of Results
- Tumor Cells, Cultured
- Vault Ribonucleoprotein Particles