Article
Spontaneous and induced minisatellite instability.
Electrophoresis - 1 Aug 1997
Jeffreys A J, Bois P, Buard J, Collick A, Dubrova Y, Hollies C R, May C A, Murray J, Neil D L, Neumann R, Stead J D, Tamaki K, Yardley J
Abstract excerpt
Minisatellites provide not only the basis for DNA fingerprinting and DNA profiling but also extremely informative systems for analysing processes of tandem repeat turnover in the human genome. Minisatellite instability appears to involve distinct mutation processes in somatic and germline cells; in the germline, mutation is frequently dominated by inter-allelic conversion-like events most likely occurring at...
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