Article
Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies.
Oncogene - 13 Oct 2003
Niwa Ohtsura
Abstract excerpt
Many studies confirmed that radiation induces genomic instability in whole-body systems. However, the results of the studies are not always consistent with each other. Attempts are made in the present review to resolve the discrepancies. Many of the studies in human and experimental animals utilize the length change mutation of minisatellite sequences as a marker of genomic instability. Minisatellite sequences...
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