Article
Deregulation of cell cycle control in hematologic malignancies.
Current opinion in hematology - 1 Jul 1996
Clurman B E, Roberts J M, Groudine M
Abstract excerpt
Cell cycle progression is governed by a complex network of positive and negative regulatory molecules. Mutations in cell cycle regulatory proteins occur frequently in tumor cells and defective cell cycle control is a common and perhaps universal feature of malignant transformation. This review ou...
Topics
- Cell Cycle
- G1 Phase
- Hematologic Neoplasms
- Humans
- Mutation