Article
Molecular aspects of the mammalian cell cycle and cancer.
The oncologist - 1 Jan 2002
Sandal T
Abstract excerpt
Cancer arises mainly from mutations in somatic cells. However, it is not the result of a single mutation, rather, it results from increasing genetic disarray accumulated over time. Tumorigenesis in humans is, therefore, a multistep and age-dependent process. The multiple mechanisms and multiple players involved in this process necessitate an understanding of the molecular mechanisms, in order to distinctively...
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