6-N-hydroxylaminopurine (HAP)-induced accumulation of variability in haploid and diploid strains of Aspergillus nidulans.

doi:10.1007/s002940050285

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Article

6-N-hydroxylaminopurine (HAP)-induced accumulation of variability in haploid and diploid strains of Aspergillus nidulans.

Current genetics - 1 Nov 1997

Pimpinelli S, Marini A, Babudri N, Morpurgo G

Abstract excerpt

Haploid and diploid strains of Aspergillus nidulans have been repeatedly treated with the strong mutagen 6-N-hydroxylaminopurine (HAP) which causes only base substitutions. An enormous amount of variability may be rapidly accumulated in haploid or diploid strains of A. nidulans. In particular, in...

Topics

Adenine
Aspergillus nidulans
Diploidy
Genes, Fungal
Genes, Lethal
Genes, Recessive
Genetic Variation
Haploidy
Mutagens
Mutation

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