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Article

Molecular characterization of four induced alleles at the Ednrb locus.

Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 1997

Shin M K, Russell L B, Tilghman S M

Abstract excerpt

The piebald locus on mouse chromosome 14 encodes the endothelin-B receptor (EDNRB), a G protein-coupled, seven-transmembrane domain protein, which is required for neural crest-derived melanocyte and enteric neuron development. A spontaneous null allele of Ednrb results in homozygous mice that are predominantly white and die as juveniles from megacolon. To identify the important domains for EDNRB function, four...

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Identifiers

PMID: 9371807
DOI: 10.1073/pnas.94.24.13105
PMCID: PMC24270

Genes

EDNRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular characterization of four induced alleles at the Ednrb locus.PMID 9371807Read ↗

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