Article
Molecular characterization of four induced alleles at the Ednrb locus.
Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 1997
Shin M K, Russell L B, Tilghman S M
Abstract excerpt
The piebald locus on mouse chromosome 14 encodes the endothelin-B receptor (EDNRB), a G protein-coupled, seven-transmembrane domain protein, which is required for neural crest-derived melanocyte and enteric neuron development. A spontaneous null allele of Ednrb results in homozygous mice that are...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Germ-Line Mutation
- Mice
- Mice, Inbred C57BL
- Mutagens
- Point Mutation
- RNA, Messenger
- Receptor, Endothelin B
- Receptors, Endothelin