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Article

Macrolide resistance in Helicobacter pylori: mechanism and stability in strains from clarithromycin-treated patients.

Antimicrobial agents and chemotherapy - 1 Nov 1997

Hultén K, Gibreel A, Sköld O, Engstrand L

Abstract excerpt

Helicobacter pylori strains from seven patients treated with clarithromycin were investigated for development, mechanism, and stability of resistance. Genetic relatedness between pre- and posttreatment isolates was shown by arbitrary primed PCR. Clarithromycin resistance was associated with A-to-G transitions at either position 2143 or 2144 or at both positions 2116 and 2142. In four cases, the mutations were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9371366
DOI: 10.1128/AAC.41.11.2550
PMCID: PMC164161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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