Article
Genotypic characterization of clarithromycin-resistant and -susceptible Helicobacter pylori strains from the same patient demonstrates existence of two unrelated isolates.
Journal of clinical microbiology - 1 Sept 1998
Wang G, Jiang Q, Taylor D E
Abstract excerpt
Clarithromycin-susceptible and clarithromycin-resistant Helicobacter pylori isolates from the same patient were investigated for the mode of development and mechanism of clarithromycin resistance. The clarithromycin-resistant strain UA1182 harbors homozygous A-to-G mutations at position 2143 in b...
Topics
- Anti-Bacterial Agents
- Clarithromycin
- Drug Resistance, Microbial
- Electrophoresis, Gel, Pulsed-Field
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Phenotype
- Point Mutation
- RNA, Bacterial
- RNA, Ribosomal, 23S