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Article

Trends in Helicobacter pylori resistance to clarithromycin: from phenotypic to genomic approaches.

Microbial genomics - 1 Mar 2020

Marques Andreia T, Vítor Jorge M B, Santos Andrea, Oleastro Mónica, Vale Filipa F

Abstract excerpt

For a long time Helicobacter pylori infections have been treated using the macrolide antibiotic, clarithromycin. Clarithromycin resistance is increasing worldwide and is the most common cause of H. pylori treatment failure. Here we review the mechanisms of antibiotic resistance to clarithromycin, detailing the individual and combinations of point mutations found in the 23S rRNA gene associated with resistance....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32118532
DOI: 10.1099/mgen.0.000344
PMCID: PMC7200067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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