Article
Isolation and characterization of invasive and noninvasive variants of a rat bladder tumor cell line.
Japanese journal of cancer research : Gann - 1 Sept 1997
Nishi N, Inui M, Kishi Y, Miyanaka H, Wada F
Abstract excerpt
We isolated, in vitro, spontaneous variants of the rat bladder tumor NBT-II cell line with a distinctive morphology. Of five sublines obtained, three (NBT-L1, L2a and L2b) exhibited an elongated shape and moderate to high invasive activity in vitro. The other two sublines (NBT-T1 and T2) formed t...
Topics
- Animals
- Cadherins
- Cell Movement
- Clone Cells
- Culture Media, Conditioned
- Cytoskeletal Proteins
- Genetic Variation
- Growth Substances
- Neoplasm Invasiveness
- RNA, Messenger
- Rats
- Receptors, Growth Factor
- Trans-Activators
- Transcription, Genetic
- Transforming Growth Factor alpha
- Tumor Cells, Cultured
- Urinary Bladder Neoplasms
- alpha Catenin