Article
Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells.
Molecular biology of the cell - 1 Aug 1994
Savagner P, Vallés A M, Jouanneau J, Yamada K M, Thiery J P
Abstract excerpt
We described previously that acidic fibroblast growth factor (aFGF), but not basic fibroblast growth factor (bFGF), can induce the rat carcinoma cell line NBT-II to undergo a rapid and reversible transition from epithelial to mesenchymal phenotype (EMT). We now find that NBT-II EMT is stimulated...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Primers
- Epithelium
- Gene Expression Regulation, Neoplastic
- Humans
- Mesoderm
- Mice
- Molecular Sequence Data
- Phenotype
- RNA, Messenger
- Rats
- Receptor Protein-Tyrosine Kinases