Article
A model for 3-dimensional growth of bladder cancers to investigate cell-matrix interactions.
Urologic oncology - 1 Jan 2000
Kyker Kimberly D, Culkin Daniel J, Hurst Robert E
Abstract excerpt
Elucidating the mechanisms by which the phenotype of cancer cells is modulated by the extracellular matrix (ECM) potentially identifies mechanisms that could be exploited for cancer control. Three readily available bladder cancer cell lines of different aggressiveness were grown on a bioscaffold material (Small Intestine Submucosa: SIS) under a variety of media and nutrient schedules to determine the influence of...
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