Article
Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p.
The Journal of biological chemistry - 21 Nov 1997
Haak D, Gable K, Beeler T, Dunn T
Abstract excerpt
The Saccharomyces cerevisiae SCS7 and SUR2 genes are members of a gene family that encodes enzymes that desaturate or hydroxylate lipids. Sur2p is required for the hydroxylation of C-4 of the sphingoid moiety of ceramide, and Scs7p is required for the hydroxylation of the very long chain fatty ac...
Topics
- Calcium
- Ceramides
- Fatty Acids, Unsaturated
- Gene Deletion
- Hydroxylation
- Mixed Function Oxygenases
- Neoplasm Proteins
- Phenotype
- Protein Kinases
- Proto-Oncogene Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sphingolipids
- Suppression, Genetic