Article
Loss of hydroxyl groups from the ceramide moiety can modify the lateral diffusion of membrane proteins in S. cerevisiae.
Journal of lipid research - 1 Jul 2014
Uemura Satoshi, Shishido Fumi, Tani Motohiro, Mochizuki Takahiro, Abe Fumiyoshi, Inokuchi Jin-Ichi
Abstract excerpt
In the yeast Saccharomyces cerevisiae, structural diversities of complex sphingolipids [inositol phosphorylceramide (IPC), mannosylinositol phosphorylceramide, and mannosyldiinositol phosphorylceramide] are often observed in the presence or absence of hydroxyl groups on the C-4 position of long-chain base (C4-OH) and the C-2 position of very long-chain fatty acids (C2-OH), but the biological significance of these...
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