Article
Abnormalities of apolipoprotein E in the acquired immunodeficiency syndrome.
The Journal of clinical endocrinology and metabolism - 1 Nov 1997
Grunfeld C, Doerrler W, Pang M, Jensen P, Weisgraber K H, Feingold K R
Abstract excerpt
Given the important role of apolipoprotein E (apoE) in triglyceride metabolism, we analyzed plasma levels and degree of sialylation of apoE in subjects with the acquired immunodeficiency syndrome (AIDS), a disorder accompanied by hypertriglyceridemia. Levels of apoE were significantly increased (1.84-fold) and correlated with plasma triglycerides (r = .663, P < .001) in AIDS. Subjects with AIDS and the apoE3/E2...
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