Sample size required for predefined linkage decision quality.

doi:10.1002/(SICI)1098-2272(1997)14:5<479::AID-GEPI3>3.0.CO;2-X

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Sample size required for predefined linkage decision quality.

Genetic epidemiology - 1 Jan 1997

Ginsburg E K, Axenovich T I

Abstract excerpt

A method for estimating the sample size required to attain a predefined linkage decision quality (type I and type II errors) is proposed using the linkage test power estimate developed by Ginsburg et al. [(1996) Genet Epidemiol 13:355-366]. The method is applicable for samples of arbitrarily structured pedigrees collected via proband. Comparison of different ascertainment schemes and pedigree structures by their...

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Sample size required for predefined linkage decision quality.

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