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Article

CADM1 regelates the G1/S transition and represses tumorigenicity through the Rb-E2F pathway in hepatocellular carcinoma

1 Jun 2016

Abstract excerpt

BACKGROUND: Increasing evidence indicates that downregulation of cell adhesion molecule 1 (CADM1) contributes to tumorigenesis in various cancers. The present study was undertaken to investigate the CADM1 expression pattern in human hepatocellular carcinoma (HCC), and to elucidate the mechanism underlying CADM1-mediated tumor suppression. METHODS: CADM1 expression in HCC cell lines was measured by quantitative...

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PMID: 27298105
DOI: 10.1016/s1499-3872(16)60099-1

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