Article
Attenuation, persistence, and vaccine potential of an Edwardsiella ictaluri purA mutant.
Infection and immunity - 1 Nov 1997
Lawrence M L, Cooper R K, Thune R L
Abstract excerpt
In this study, an adenine-auxotrophic strain of Edwardsiella ictaluri was constructed and its virulence, tissue persistence, and vaccine efficacy were evaluated. A clone containing the purA gene was isolated from an E. ictaluri genomic library, sequenced, and shown to have an overall sequence ide...
Topics
- Animals
- Bacterial Vaccines
- Base Sequence
- Enterobacteriaceae
- Ictaluridae
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Vaccines, Attenuated