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Article

Attenuation, persistence, and vaccine potential of an Edwardsiella ictaluri purA mutant.

Infection and immunity - 1 Nov 1997

Lawrence M L, Cooper R K, Thune R L

Abstract excerpt

In this study, an adenine-auxotrophic strain of Edwardsiella ictaluri was constructed and its virulence, tissue persistence, and vaccine efficacy were evaluated. A clone containing the purA gene was isolated from an E. ictaluri genomic library, sequenced, and shown to have an overall sequence identity of 79.3% at the nucleotide level and 85.7% at the amino acid level with the Escherichia coli purA gene. The...

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Identifiers

PMID: 9353045
DOI: 10.1128/iai.65.11.4642-4651.1997
PMCID: PMC175666

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