Article
Sunlight and the onset of skin cancer.
Trends in genetics : TIG - 1 Oct 1997
Brash D E
Abstract excerpt
The photons of sunlight precipitate a series of genetic events in skin leading to cancer. These events involve somatic mutations as well as inherited alleles. Competition between cell populations ensues, as a single mutated cell expands into a clone. Thus cancer involves both a single-cell problem and a many-cell problem; in skin cancer, sunlight appears to drive both.
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