Article
Error rate for HLA-B antigen assignment by serology: implications for proficiency testing and utilization of DNA-based typing methods.
Tissue antigens - 1 Oct 1997
Bozón M V, Delgado J C, Selvakumar A, Clavijo O P, Salazar M, Ohashi M, Alosco S M, Russell J, Yu N, Dupont B, Yunis E J
Abstract excerpt
Until recently, the majority of HLA class I typing has been performed by serology. Expensive commercial typing trays are frequently used for testing non-Caucasian subjects and new strategies using DNA-based methods have been adopted for improving clinical histocompatibility testing results and ad...
Topics
- DNA
- DNA Primers
- DNA Probes, HLA
- Diagnostic Errors
- Evaluation Studies as Topic
- Genes, MHC Class I
- Genotype
- HLA-B Antigens
- Histocompatibility Testing
- Humans
- Polymerase Chain Reaction
- Racial Groups
- Reagent Kits, Diagnostic
- Sensitivity and Specificity