Quantification and genotyping of serum HCV-RNA in patients with chronic hepatitis C undergoing interferon treatment.

doi:10.1007/s007050050092

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Article

Quantification and genotyping of serum HCV-RNA in patients with chronic hepatitis C undergoing interferon treatment.

Archives of virology - 1 Jan 1997

Gerken G, Knolle P, Jakobs S, Meyer zum Büschenfelde K H

Abstract excerpt

Quantification of serum HCV-RNA and HCV genotyping was studied in 27 patients with chronic hepatitis C undergoing interferon treatment. Pretreatment serum HCV-RNA levels were quantified using competitive RT-PCR and compared to a quantitative RT-PCR assay based on co-amplification of HCV-RNA with a synthetic RNA standard. HCV genotyping was performed using a line probe reversed hybridisation assay or direct...

Topics

Adult
Aged
Antiviral Agents
Evaluation Studies as Topic
Female
Follow-Up Studies
Genotype
Hepacivirus
Hepatitis C, Chronic
Humans
Interferon alpha-2
Interferon-alpha
Male
Middle Aged
Polymerase Chain Reaction
RNA, Viral
Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 9349292
DOI: 10.1007/s007050050092

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