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Article

Quantitation of hepatic hepatitis C virus RNA in patients with chronic hepatitis C. Relationship with severity of disease, viral genotype and response to treatment.

Journal of hepatology - 1 Sept 2001

Gervais A, Martinot M, Boyer N, Auperin A, Le Breton W, Degott C, Valla D, Marcellin P

Abstract excerpt

BACKGROUND/AIMS: To determine the correlation between hepatic hepatitis C virus (HCV) RNA and histological lesions, viral genotype or response to alpha interferon therapy. METHODS: Forty-three patients with chronic hepatitis C (14 sustained responders (SR) and 29 non-sustained responders (NSR)) were studied. A liver tissue sample was obtained before and 1 year after treatment. Quantitation of hepatic HCV-RNA was...

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PMID: 11592602
DOI: 10.1016/s0168-8278(01)00138-6

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