Article
[Ataxia-telangiectasia and cancer: an open question].
Bulletin du cancer - 1 Jul 1997
Rodriguez C, Theillet C
Abstract excerpt
Ataxia-telangiectasia is a rare recessive disorder which, among other clinical signs, is characterized by an extreme sensitivity to ionising radiation. Cells isolated from AT patients show radioresistant DNA synthesis and this has lead to the hypothesis that the product of the genetic determinant...
Topics
- Adult
- Ataxia Telangiectasia
- Ataxia Telangiectasia Mutated Proteins
- Breast Neoplasms
- Cell Cycle Proteins
- Chromosomes, Human, Pair 11
- DNA-Binding Proteins
- Female
- Genes, Neoplasm
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Mutation
- Neoplasms
- Phenotype
- Protein Serine-Threonine Kinases
- Proteins
