Article
Interferon-alpha 2 variants in the human genome.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Apr 1995
Lee N, Ni D, Brissette R, Chou M, Hussain M, Gill D S, Liao M J, Testa D
Abstract excerpt
Variants of human leukocyte interferon alpha 2 (IFN-alpha 2a, alpha 2b, and alpha 2c) differ from each other by changes in their coding regions at nucleotide positions 137 and 170. As a result of these nucleotide variations, the DNA sequences of the three variants can be distinguished by selectiv...
Topics
- Alleles
- Base Sequence
- DNA
- Genetic Variation
- Genome, Human
- Humans
- Interferon Type I
- Leukocytes
- Molecular Sequence Data
- Polymerase Chain Reaction
- Reference Values
- Restriction Mapping
- Tumor Cells, Cultured
