Article
Determination of interferon-alpha2 allele composition in the genomic DNA from healthy volunteers and leukemic patients in Japan.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Mar 1997
Kita M, Tanaka K, Uoshima N, Kobayashi Y, Ozawa M, Kondo M, Imanishi J
Abstract excerpt
The three interferon-alpha2 (IFN-alpha2) sequences identified to date differ from each other in just two nucleotide positions, both of which result in changes in amino acids. Thus, the mature IFN-alpha2a protein product is characterized by a lysine residue at position 23 (AAA) and a histidine at...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- Case-Control Studies
- Cell Line
- DNA
- DNA, Neoplasm
- Female
- Genome, Human
- Humans
- Interferon Type I
