Article
Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.
The Journal of cell biology - 20 Oct 1997
Straub V, Rafael J A, Chamberlain J S, Campbell K P
Abstract excerpt
Genetic defects in a number of components of the dystrophin-glycoprotein complex (DGC) lead to distinct forms of muscular dystrophy. However, little is known about how alterations in the DGC are manifested in the pathophysiology present in dystrophic muscle tissue. One hypothesis is that the DGC protects the sarcolemma from contraction-induced damage. Using tracer molecules, we compared sarcolemmal integrity in...
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