Article
Dystrophin-deficient zebrafish feature aspects of the Duchenne muscular dystrophy pathology.
Neuromuscular disorders : NMD - 1 Dec 2010
Berger Joachim, Berger Silke, Hall Thomas E, Lieschke Graham J, Currie Peter D
Abstract excerpt
Duchenne muscular dystrophy is caused by mutations in the dystrophin gene. As in humans, zebrafish dystrophin is initially expressed at the peripheral ends of the myofibres adjacent to the myotendinous junction and gradually shifts to non-junctional sites. Dystrophin-deficient zebrafish larvae ar...
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