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Article

Progress of emphysema in severe alpha 1-antitrypsin deficiency as assessed by annual CT.

Acta radiologica (Stockholm, Sweden : 1987) - 1 Sept 1997

Dirksen A, Friis M, Olesen K P, Skovgaard L T, Sørensen K

Abstract excerpt

PURPOSE: To assess serial CT as a measure of the progress of emphysema in patients with severe alpha 1-antitrypsin deficiency (phenotype PiZ). MATERIAL AND METHODS: In a randomized placebo-controlled study of alpha 1-antitrypsin augmentation therapy, 22 patients with moderate emphysema were followed for 2-4 years with an annual lung CT. The images were analysed by means of semiautomatic lung detection, and the...

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Identifiers

PMID: 9332238
DOI: 10.1080/02841859709172418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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