Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The appearance of the CD4+CD8+ phenotype on activated T cells: possible role of antigen transfer.

Human immunology - 1 Jun 1997

Rabinowitz R, Hadar R, Schlesinger M

Abstract excerpt

Stimulation of peripheral blood lymphocytes (PBL) with phytohemagglutinin (PHA) strikingly increased the proportion of CD4+CD8+ cells. Highly purified CD4+ and CD8+ lymphocyte populations cultured in the presence of PHA consistently failed to coexpress the CD8 and CD4 markers. Similarly, exposure of highly purified CD4+ cells to PHA and recombinant interleukin-2 resulted in augmented expression of CD25 but failed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to CD4 Antigens
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD8 Antigens

Share to Flow Cytometry

Share to Lymphocyte Activation

Share to Phenotype

Share to T-Lymphocyte Subsets

Source

Identifiers

PMID: 9328784
DOI: 10.1016/s0198-8859(97)00073-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

The appearance of the CD4+CD8+ phenotype on activated T cells: possible role of antigen transfer.PMID 9328784Read ↗

Co-cultivation of CD4+ and CD8+ human T-cells leads to the appearance of CD4 cells expressing CD8 through de novo synthesis of the CD8 alpha-subunit.Semantic proximity Read ↗

Surface phenotypes of human T cell lines generated after WGA- and PHA-stimulation.Semantic proximity Read ↗

Ligation of MHC class I molecules on peripheral blood T lymphocytes induces new phenotypes and functions.Semantic proximity Read ↗

Phenotypic characteristics of T cells interacted with synovial cells.Semantic proximity Read ↗

Functional and phenotypic changes in human lymphocytes after coincubation with Leishmania donovani in vitro.Semantic proximity Read ↗

Surface markers on human activated T lymphocytes. IV. Comparison of high-affinity E-rosette receptor expression with the expression of other activation markers (receptor for interleukin 2, MHC class II (antigens).Semantic proximity Read ↗

CD11b+CD28-CD4+ human T cells: activation requirements and association with HLA-DR alleles.Semantic proximity Read ↗

Discrimination between thymic epithelial cells and peripheral antigen-presenting cells in the induction of immature T cell differentiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.