Article
Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19.
Human molecular genetics - 1 Nov 1997
Semina E V, Reiter R S, Murray J C
Abstract excerpt
We recently reported the positional cloning of a homeobox gene involved in the pathogenesis of Rieger syndrome, RIEG1 , and its mouse homolog, Rieg1 . Rieg1 (also independently described as Pitx2) is highly homologous to the Ptx1/Potx gene product, suggesting that there may be additional members of this novel Pitx family. The Pitx genes play an important role in eye, tooth, pituitary and umbilical region...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.