[Methods for the evaluation of the mutagenic and genotoxic properties of chemical compounds. III. The sister chromatid exchange test in vivo (an abbreviated method)].

Article

[Methods for the evaluation of the mutagenic and genotoxic properties of chemical compounds. III. The sister chromatid exchange test in vivo (an abbreviated method)].

Medycyna pracy - 1 Jan 1992

Wyszyńska K, Chwiałkowska-Liro W

Abstract excerpt

The principle and experimental procedure of the in vivo sister chromatid exchange (SCE) test applied in the screening of chemical compounds for their mutagenic properties are presented. The objective of this assay is to evaluate the ability of a test chemical to induce SCE in bone marrow cells of...

Topics

Animals
Bone Marrow
Bromodeoxyuridine
Chromosomes
Drug Implants
Male
Mice
Models, Genetic
Mutagenicity Tests
Mutation
Sister Chromatid Exchange
Staining and Labeling

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