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[The cytogenetic effect of cyclophosphane and the formation of active forms of oxygen in the bone marrow cells of C57Bl/6 and NZW mice].

Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2000

Guseva N V, Durnev A D, Pleskovskaia G N, Seredenin S B

Abstract excerpt

Cytogenetic study conducted after a single intraperitoneal injection of cyclophosphane in doses of 10, 20, and 40 mg/kg showed in 1.5-2-month-old male mice that the level of bone marrow cells damaged by the mutagen was significantly higher in NZW animals than in C57Bl/6 animals. The ability to produce active oxygen forms in response to addition of opsonized zymosan and phorbol myristate acetate was also higher in...

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PMID: 9690081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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