Article
H‐<i>ras</i> oncogene point mutations in arthritic synovium
1 Sept 1997
Abstract excerpt
OBJECTIVE: To examine mutational activation of ras proto-oncogenes in synovial tissue from patients with rheumatoid arthritis (RA) compared with synovial specimens from patients with osteoarthritis (OA) or other arthropathies. Synovial samples from cadavers, without any signs of joint disease, were used as control material. METHODS: Using a combination of polymerase chain reaction (PCR) and automated sequencing...
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