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Article

CDC5 and CKII control adaptation to the yeast DNA damage checkpoint.

Cell - 19 Sept 1997

Toczyski D P, Galgoczy D J, Hartwell L H

Abstract excerpt

A single double-stranded DNA (dsDNA) break will cause yeast cells to arrest in G2/M at the DNA damage checkpoint. If the dsDNA break cannot be repaired, cells will eventually override (that is, adapt to) this checkpoint, even though the damage that elicited the arrest is still present. Here, we report the identification of two adaptation-defective mutants that remain permanently arrested as large-budded cells...

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Identifiers

PMID: 9323137
DOI: 10.1016/s0092-8674(00)80375-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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