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Article

Rethinking progesterone regulation of female reproductive cyclicity.

Proceedings of the National Academy of Sciences of the United States of America - 12 Apr 2016

Kubota Kaiyu, Cui Wei, Dhakal Pramod, Wolfe Michael W, Rumi M A Karim, Vivian Jay L, Roby Katherine F, Soares Michael J

Abstract excerpt

The progesterone receptor (PGR) is a ligand-activated transcription factor with key roles in the regulation of female fertility. Much has been learned of the actions of PGR signaling through the use of pharmacologic inhibitors and genetic manipulation, using mouse mutagenesis. Characterization of rats with a null mutation at the Pgr locus has forced a reexamination of the role of progesterone in the regulation of...

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Identifiers

PMID: 27035990
DOI: 10.1073/pnas.1601825113
PMCID: PMC4839436

Genes

PGR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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