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Article

Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis.

Infection and immunity - 1 Oct 1997

Storey D G, Ujack E E, Mitchell I, Rabin H R

Abstract excerpt

Pseudomonas aeruginosa causes a chronic infection in the lungs of individuals with cystic fibrosis. The P. aeruginosa isolates from these infections, when grown under laboratory conditions, characteristically are mucoid and produce low levels of the more destructive virulence factors, such as exotoxin A and the proteases. We wanted to determine if during the chronic lung infections associated with CF, the...

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Identifiers

PMID: 9317008
DOI: 10.1128/iai.65.10.4061-4067.1997
PMCID: PMC175584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Positive correlation of algD transcription to lasB and lasA transcription by populations of Pseudomonas aeruginosa in the lungs of patients with cystic fibrosis.PMID 9317008Read ↗

Population transcript accumulation of Pseudomonas aeruginosa exotoxin A and elastase in sputa from patients with cystic fibrosisSemantic proximity Read ↗

Global Genomic Analysis of AlgU (σ E )-Dependent Promoters (Sigmulon) in Pseudomonas aeruginosa and Implications for Inflammatory Processes in Cystic FibrosisSemantic proximity Read ↗

Pseudomonas aeruginosa AlgB, a two-component response regulator of the NtrC family, is required for algD transcriptionSemantic proximity Read ↗

Transcriptional analysis of the Pseudomonas aeruginosa genes algR, algB, and algD reveals a hierarchy of alginate gene expression which is modulated by algT.Semantic proximity Read ↗

Pseudomonas aeruginosa AlgB, which modulates the expression of alginate, is a member of the NtrC subclass of prokaryotic regulators.Semantic proximity Read ↗

Pseudomonas aeruginosa AlgZ, a ribbon-helix-helix DNA-binding protein, is essential for alginate synthesis and algD transcriptional activation.Semantic proximity Read ↗

DNA sequence and expression analysis of algP and algQ, components of the multigene system transcriptionally regulating mucoidy in Pseudomonas aeruginosa: algP contains multiple direct repeats.Semantic proximity Read ↗

Identification and characterization of AlgZ, an AlgT-dependent DNA-binding protein required for Pseudomonas aeruginosa algD transcription.Semantic proximity Read ↗

Role of an alginate lyase for alginate transport in mucoid Pseudomonas aeruginosa.Semantic proximity Read ↗

The algT (algU) gene of Pseudomonas aeruginosa, a key regulator involved in alginate biosynthesis, encodes an alternative sigma factor (sigma E).Semantic proximity Read ↗

lasA and lasB genes of Pseudomonas aeruginosa: analysis of transcription and gene product activity.Semantic proximity Read ↗

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