Spontaneous Activation of Ovulated Mouse Eggs: Time-dependent Effects on M-phase Exit, Cortical Granule Exocytosis, Maternal Messenger Ribonucleic Acid Recruitment, and Inositol 1,4,5-trisphosphate Sensitivity1

Abstract excerpt

With increasing time after ovulation, mammalian eggs become more sensitive to agonists of activation in vitro or may undergo spontaneous activation in vivo. We have tested the hypothesis that postovulatory eggs undergo time-dependent cell cycle and cytoplasmic changes that result in a partially activated state, accounting for their time-dependent susceptibility to activate. In vivo changes in key activation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animal Genetics and Reproduction
• Share to Birth, Development, and Health
• Share to Reproductive Biology and Fertility